What is the primary consequence of untreated Kawasaki disease?

Untreated Kawasaki disease primarily leads to coronary artery damage, which is a critical concern for patients suffering from this condition. Kawasaki disease is an acute febrile illness that predominantly affects children and is characterized by inflammation of the blood vessels, particularly those supplying the heart. The inflammation can result in the formation of aneurysms in the coronary arteries, which can compromise blood flow to the heart muscle and lead to serious complications such as myocardial ischemia or infarction.

If left untreated, the risk of these complications significantly increases, making early diagnosis and treatment vital in managing Kawasaki disease to prevent long-term cardiovascular problems. Typically, treatment involves administering high-dose aspirin and intravenous immunoglobulin (IVIG) to reduce inflammation and prevent coronary artery involvement.

Understanding the primary consequence of untreated Kawasaki disease helps in recognizing the importance of prompt medical intervention to safeguard against permanent damage to the cardiovascular system.